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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T60539 KG-548

KG-548 是一种ARNT/TACC3干扰剂以及HIF-1α抑制剂。KG-548 通过 ARNT 的 PAS-B 结构域与 TACC3 竞争性结合,直接干扰ARNT/TACC3复合物的形成。ARNT 是芳基烃受体核转运蛋白,也称为 HIF-β。

化合物

KG-548
Cat.No: T60539
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-00957 ARNT Protein, Human, Recombinant (His)

Hypoxia-inducible factor 1-beta,Class E basic helix-loop-hel...

Human P. pastoris (Yeast)
ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His)

bHLHe78,HIF-1 α,hypoxia inducible factor 1, alpha subunit (b...

Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has...

重组蛋白

ARNT Protein, Human, Recombinant (His)
Cat.No: TMPH-00957
Species: Human
Expression System: P. pastoris (Yeast)
HIF-1 alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-01709
Species: Human
Expression System: E. coli
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